4x7q A 2.33 BS01 3YR A 1 F43 V46 A59 K61 E117 A122 D124 E167 L170 I181 D182 F12 V15 A24 K26 E57 A62 D64 E107 L110 I121 D122 D163 K165 N168 D182 T200 D103 K105 N108 D122 T130 2.7.11.1 0000082,0004672,0004674,0005515,0005524,0005737,0006338,0006468,0006915,0007346,0008285,0008637,0009615,0010508,0016236,0016239,0016310,0043066,0043123,0044024,0045893,0050821,0106310 ic50=14nM IC50=14nM Q9P1W9 25575657 401 YRLGPLLGKGGFGTVFAGHRLQVAIKVIPRLEVALLWKVGHPGVIRLLDWFFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGADGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ 4x7q B 2.33 BS01 3YR B 1 F43 V46 A59 K61 E117 R118 A122 D124 E167 L170 I181 D182 F16 V19 A32 K34 E73 R74 A78 D80 E123 L126 I137 D138 D163 K165 N168 D182 T200 D119 K121 N124 D138 T156 2.7.11.1 0000082,0004672,0004674,0005515,0005524,0005737,0006338,0006468,0006915,0007346,0008285,0008637,0009615,0010508,0016236,0016239,0016310,0043066,0043123,0044024,0045893,0050821,0106310 ic50=14nM -logKd/Ki=7.85, IC50=14nM IC50=14nM Q9P1W9 25575657 401 AFEAEYRLGPLLGKGFGTVFAGHRLTDRLQVAIKVIPRCPLEVALLWKVGAGGGHPGVIRLLDWFETFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ