4x6x A 1.8 BS01 S74 A 1 F267 D335 W336 P361 I363 Y383 F387 M419 Y466 V498 L499 M503 H524 W525 F38 D106 W107 P132 I134 Y154 F158 M190 Y237 V269 L270 M274 H295 W296 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F38 H105 D106 W107 N130 N149 Y154 Y237 D267 H295 3.1.3.76,3.3.2.10 0003824 ic50=2.3nM -logKd/Ki=8.64, IC50=2.3nM IC50=2.3nM P34913 25800114 601 TSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSD 4x6x B 1.8 BS01 S74 B 1 F267 D335 M339 Y383 F387 M419 Y466 V498 H524 W525 F38 D106 M110 Y154 F158 M190 Y237 V269 H295 W296 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F38 H105 D106 W107 N130 N149 Y154 Y237 D267 H295 3.1.3.76,3.3.2.10 0003824 ic50=2.3nM IC50=2.3nM P34913 25800114 601 TSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSD