4x4l A 1.85 BS01 3XG A 1 S121 M175 W178 Y297 G458 F466 S113 M167 W170 Y289 G450 F458 N170 K193 E269 C303 E400 E477 N162 K185 E261 C295 E392 E469 1.2.1.19,1.2.1.28,1.2.1.3,1.2.1.36 0000166,0001523,0001758,0004029,0005096,0005497,0005515,0005737,0005829,0006081,0006629,0009449,0016491,0016620,0018479,0019145,0030392,0030424,0036438,0042572,0042995,0045202,0051287,0070062,0106373,0110095,0120163 ic50=4.6uM IC50=20nM, EC50=3040nM, Ki=230nM P00352 25634381 603 LPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS 4x4l A 1.85 BS02 NAI A 1 I166 I167 P168 W169 K193 E196 G226 G230 F244 T245 G246 S247 V250 C303 Q350 K353 E400 F402 I158 I159 P160 W161 K185 E188 G218 G222 F236 T237 G238 S239 V242 C295 Q342 K345 E392 F394 N170 K193 E269 C303 E400 E477 N162 K185 E261 C295 E392 E469 1.2.1.19,1.2.1.28,1.2.1.3,1.2.1.36 0000166,0001523,0001758,0004029,0005096,0005497,0005515,0005737,0005829,0006081,0006629,0009449,0016491,0016620,0018479,0019145,0030392,0030424,0036438,0042572,0042995,0045202,0051287,0070062,0106373,0110095,0120163 P00352 25634381 608 LPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS