4wa9 A 2.2 BS01 AXI A 1 L248 Y253 A269 K271 F317 M318 T319 G321 L370 A380 F382 L13 Y18 A34 K36 F59 M60 T61 G63 L112 A122 F124 D363 A365 R367 N368 D381 P402 D105 A107 R109 N110 D123 P144 2.7.10.2 0004672,0004713,0005524,0006468 Ki=3800pM P00519 25686603 9000 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKEIKHPNLVQLLGVCTREPIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISD 4wa9 B 2.2 BS01 AXI B 1 Y253 V256 A269 K271 E316 F317 M318 G321 L370 A380 F382 Y21 V24 A37 K39 E84 F85 M86 G89 L138 A148 F150 D363 A365 R367 N368 D381 P402 D131 A133 R135 N136 D149 P170 2.7.10.2 0004672,0004713,0005524,0006468 Ki=3800pM -logKd/Ki=8.42, Ki=3800pM P00519 25686603 9000 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEK