4uzd A 3.2 BS01 QMN A 1 V147 K162 L178 Q185 L194 L208 L210 Y212 A213 A273 F275 V21 K36 L52 Q59 L68 L82 L84 Y86 A87 A147 F149 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T158 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=9.22, IC50=0.6nM IC50=0.600000nM, EC50=106nM O14965 25369539 1389 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4uzd B 3.2 BS01 QMN B 1 K141 V147 A160 K162 L178 Q185 L194 L208 E211 Y212 A213 A273 F275 G276 K17 V23 A36 K38 L54 Q61 L70 L84 E87 Y88 A89 A149 F151 G152 D256 K258 E260 N261 D274 T292 D132 K134 E136 N137 D150 T161 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=9.22, IC50=0.6nM IC50=0.600000nM, EC50=106nM O14965 25369539 1390 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK