4uxb A 3.22 BS01 P34 A 1 H862 G863 G888 Y889 Y896 S904 Y907 H182 G183 G208 Y209 Y216 S224 Y227 S904 Y907 E988 S224 Y227 E301 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=7.96, IC50=10.9nM IC50=110nM, Kd=110nM, EC50=20nM P09874 28001384 2011 MKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQDSQILDLSNRFYTLIPHDPLLNNADSVQAKAEMLDNLLDIEVAYSLLRDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHANAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHSKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4uxb B 3.22 BS01 P34 B 1 H862 G863 Y889 Y896 F897 S904 Y907 E988 H189 G190 Y216 Y223 F224 S231 Y234 E315 S904 Y907 E988 S231 Y234 E315 2.4.2.-,2.4.2.30 0003950 IC50=110nM, Kd=110nM, EC50=20nM P09874 28001384 2010 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNF