4und A 2.2 BS01 2YQ A 1 E763 H862 G863 Y889 Y896 S904 Y907 E109 H208 G209 Y235 Y242 S250 Y253 S904 Y907 E988 S250 Y253 E334 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=8.96, Kd=1.1nM Ki=1.2nM, IC50=0.570000nM, EC50=2.5nM P09874 28001384 2011 NLYFQSMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4und B 2.2 BS01 2YQ B 1 E763 H862 G863 G888 Y889 Y896 K903 S904 Y907 E102 H201 G202 G227 Y228 Y235 K242 S243 Y246 S904 Y907 E988 S243 Y246 E327 2.4.2.-,2.4.2.30 0003950 Ki=1.2nM, IC50=0.570000nM, EC50=2.5nM P09874 28001384 2011 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK