4u42 A 2.504 BS01 3C8 A 1 Y36 V39 A52 K54 L103 M105 E106 F107 C108 L160 V170 Y21 V24 A37 K39 L88 M90 E91 F92 C93 L145 V155 D153 K155 Q157 N158 D171 T191 D138 K140 Q142 N143 D156 T163 2.7.11.1 0004672,0005524,0006468 IC50=6.20nM, Ki=10.7nM O95819 402 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 A 2.504 BS02 MG A 1 S77 H78 H79 R80 I82 S62 H63 H64 R65 I67 D153 K155 Q157 N158 D171 T191 D138 K140 Q142 N143 D156 T163 2.7.11.1 0004672,0005524,0006468 O95819 403 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 B 2.504 BS01 3C8 B 1 Y36 A52 K54 M105 E106 F107 C108 L160 V170 D171 Y20 A36 K38 M71 E72 F73 C74 L126 V136 D137 D153 K155 Q157 N158 D171 T191 D119 K121 Q123 N124 D137 T146 2.7.11.1 0004672,0005524,0006468 IC50=6.20nM, Ki=10.7nM O95819 401 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTKYSHHRNIATYYGAFIKKSPPDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 B 2.504 BS02 MG B 1 S77 H78 H79 I82 T84 S46 H47 H48 I51 T53 D153 K155 Q157 N158 D171 T191 D119 K121 Q123 N124 D137 T146 2.7.11.1 0004672,0005524,0006468 O95819 402 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTKYSHHRNIATYYGAFIKKSPPDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR