4tuh A 1.8 BS01 38H A 1 A93 E96 F97 Y101 R102 F105 S106 L108 T109 L130 N136 G138 R139 A142 S145 F146 A149 Y195 A41 E44 F45 Y49 R50 F53 S54 L56 T57 L78 N84 G86 R87 A90 S93 F94 A97 Y143 ? 0042981 -logKd/Ki=4.00, IC50>100uM Ki=0.380000nM, EC50=60nM Q07817 24944740 301 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tuh B 1.8 BS01 38H B 1 E96 F97 Y101 R102 F105 S106 L108 L130 G138 R139 S145 F146 A149 L194 Y195 E45 F46 Y50 R51 F54 S55 L57 L79 G87 R88 S94 F95 A98 L143 Y144 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tuh C 1.8 BS01 38H C 1 A93 E96 F97 Y101 R102 F105 S106 L108 T109 L130 G138 R139 A142 F146 A149 Y195 A38 E41 F42 Y46 R47 F50 S51 L53 T54 L75 G83 R84 A87 F91 A94 Y140 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 4tuh D 1.8 BS01 38H D 1 A93 E96 F97 Y101 R102 F105 S106 L108 T109 L130 G138 R139 A142 S145 F146 A149 Y195 A37 E40 F41 Y45 R46 F49 S50 L52 T53 L74 G82 R83 A86 S89 F90 A93 Y139 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 4tuh E 1.8 BS01 38H E 1 A93 E96 F97 Y101 R102 F105 S106 L108 T109 L130 G138 R139 A142 S145 F146 A149 L194 Y195 A37 E40 F41 Y45 R46 F49 S50 L52 T53 L74 G82 R83 A86 S89 F90 A93 L138 Y139 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tuh F 1.8 BS01 38H F 1 A93 E96 F97 Y101 R102 F105 S106 L108 L130 N136 G138 R139 S145 F146 A149 Y195 A41 E44 F45 Y49 R50 F53 S54 L56 L78 N84 G86 R87 S93 F94 A97 Y143 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN 4tuh G 1.8 BS01 38H G 1 E96 F97 Y101 R102 F105 S106 L108 T109 L130 N136 G138 R139 A142 S145 F146 A149 L194 Y195 E41 F42 Y46 R47 F50 S51 L53 T54 L75 N81 G83 R84 A87 S90 F91 A94 L139 Y140 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tuh H 1.8 BS01 38H H 1 A93 E96 F97 Y101 R102 F105 S106 L108 T109 L130 G138 R139 A142 S145 F146 A149 Y195 A39 E42 F43 Y47 R48 F51 S52 L54 T55 L76 G84 R85 A88 S91 F92 A95 Y141 ? 0042981 Ki=0.380000nM, EC50=60nM Q07817 24944740 301 GSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN