4tjy A 1.9 BS01 ZN A 1 C1081 H1084 C1089 C1092 C120 H123 C128 C131 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy A 1.9 BS02 3GN A 1 H1031 G1032 Y1060 F1061 K1067 S1068 Y1071 E1138 H70 G71 Y99 F100 K106 S107 Y110 E177 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=6.44, IC50=0.367uM Q9H2K2 25286857 1202 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy B 1.9 BS01 ZN B 1 C1081 H1084 C1089 C1092 C125 H128 C133 C136 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 LYFQGDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy B 1.9 BS02 3GN B 1 H1031 G1032 Y1060 F1061 K1067 S1068 Y1071 I1075 E1138 H75 G76 Y104 F105 K111 S112 Y115 I119 E182 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1202 LYFQGDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy C 1.9 BS01 ZN C 1 C1081 H1084 C1089 C1092 C129 H132 C137 C140 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy C 1.9 BS02 3GN C 1 H1031 G1032 Y1060 F1061 K1067 S1068 Y1071 E1138 H79 G80 Y108 F109 K115 S116 Y119 E186 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1202 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP