4tjw A 1.7 BS01 ZN A 1 C1081 H1084 C1089 C1092 C119 H122 C127 C130 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 KEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tjw A 1.7 BS02 P34 A 1 H1031 G1032 Y1050 G1053 G1056 Y1060 F1061 K1067 S1068 Y1071 I1075 E1138 H69 G70 Y88 G91 G94 Y98 F99 K105 S106 Y109 I113 E176 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=6.02, IC50=0.963uM IC50=2951nM Q9H2K2 25286857 1202 KEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tjw B 1.7 BS01 ZN B 1 C1081 H1084 C1089 C1092 C129 H132 C137 C140 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjw B 1.7 BS02 P34 B 1 H1031 G1032 Y1050 G1052 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H79 G80 Y98 G100 Y108 F109 A110 K115 S116 Y119 I123 E185 2.4.2.-,2.4.2.30 0003950 IC50=2951nM Q9H2K2 25286857 1202 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjw C 1.7 BS01 ZN C 1 C1081 H1084 C1089 C1092 C129 H132 C137 C140 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjw C 1.7 BS02 P34 C 1 H1031 G1032 G1052 Y1060 F1061 K1067 S1068 Y1071 I1075 H79 G80 G100 Y108 F109 K115 S116 Y119 I123 2.4.2.-,2.4.2.30 0003950 IC50=2951nM Q9H2K2 25286857 1202 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjw D 1.7 BS01 ZN D 1 C1081 H1084 C1089 C1092 C117 H120 C125 C128 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1200 FQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPALAEYVIYRGEQAYPEYLITYQIMRP