4ryl A 2.1 BS01 3ZG A 1 K392 H393 R396 V420 E422 T466 A467 K150 H151 R154 V178 E180 T224 A225 D253 E346 E355 H496 D11 E104 E113 H254 2.1.1.319 0016274,0018216 Kd=53nM -logKd/Ki=7.28, Kd=53nM IC50=91nM, EC50=2000nM O60678 25728001 601 HYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKSLTVTLTLNNSTQTYGLQ