4rx7 A 1.8 BS01 3YV A 1 L377 A400 M448 E449 A451 G454 P455 R498 L501 D512 L15 A38 M83 E84 A86 G89 P90 R133 L136 D147 D494 A496 R498 N499 D512 K533 D129 A131 R133 N134 D147 K168 2.7.10.2 0004672,0004713,0005524,0006468 ic50=5nM -logKd/Ki=8.30, IC50=5nM IC50=104nM P43405 25633741 703 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVTDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNHH