4rhu A 2.573 BS01 3QE A 1 S127 G128 T130 K154 F175 V176 D182 S105 G106 T108 K132 F153 V154 D160 E122 D123 D126 F175 R188 E100 D101 D104 F153 R166 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 -logKd/Ki=6.16, Ki=0.69uM P9WHQ9 25915781 301 QTAELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRETTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu A 2.573 BS02 MG A 1 E122 D123 E100 D101 E122 D123 D126 F175 R188 E100 D101 D104 F153 R166 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 302 QTAELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRETTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu B 2.573 BS01 3QE B 1 G67 V124 D126 S127 G128 T130 K154 F175 V176 D182 R188 G52 V102 D104 S105 G106 T108 K132 F151 V152 D158 R164 E122 D123 D126 F175 R188 E100 D101 D104 F151 R164 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 -logKd/Ki=6.16, Ki=0.69uM P9WHQ9 25915781 301 AELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVNVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu B 2.573 BS02 MG B 1 E122 D123 E100 D101 E122 D123 D126 F175 R188 E100 D101 D104 F151 R164 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 302 AELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVNVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu C 2.573 BS01 45T C 1 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 D102 S103 G104 T106 K130 F151 V152 L157 D158 R164 E122 D123 D126 F175 R188 E98 D99 D102 F151 R164 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 301 LYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rhu C 2.573 BS02 MG C 1 E122 D123 E98 D99 E122 D123 D126 F175 R188 E98 D99 D102 F151 R164 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 302 LYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rhu D 2.573 BS01 45T D 1 V124 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 V93 D95 S96 G97 T99 K123 F144 V145 L150 D151 R157 E122 D123 D126 F175 R188 E91 D92 D95 F144 R157 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 301 GDIKSVLLTAEQIQARIAELGEQIGNDYREATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rhu E 2.573 BS01 45T E 1 V124 D126 S127 G128 T130 K154 F175 V176 D182 V91 D93 S94 G95 T97 K121 F142 V143 D149 E122 D123 D126 F175 R188 E89 D90 D93 F142 R155 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 301 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu E 2.573 BS02 MG E 1 E122 D123 E89 D90 E122 D123 D126 F175 R188 E89 D90 D93 F142 R155 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 302 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu F 2.573 BS01 45T F 1 L65 V124 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 L43 V94 D96 S97 G98 T100 K124 F145 V146 L151 D152 R158 E122 D123 D126 F175 R188 E92 D93 D96 F145 R158 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 301 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu F 2.573 BS02 MG F 1 E122 D123 E92 D93 E122 D123 D126 F175 R188 E92 D93 D96 F145 R158 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006177,0006178,0006188,0016757,0032263,0032264,0043101,0046100,0046872,0052657 P9WHQ9 25915781 303 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ