4qtb A 1.4 BS01 38Z A 1 A52 Y53 A69 K71 I73 Y81 R84 T85 E88 Q122 D123 M125 E126 T127 K131 L173 C183 D184 A29 Y30 A46 K48 I50 Y58 R61 T62 E65 Q99 D100 M102 E103 T104 K108 L150 C160 D161 D166 K168 S170 N171 D184 T207 D143 K145 S147 N148 D161 T184 2.7.11.24 0000165,0001784,0004672,0004674,0004707,0005515,0005524,0005634,0005635,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005829,0005856,0005886,0005901,0005925,0006351,0006468,0006915,0006974,0008286,0009887,0010759,0014032,0014044,0016020,0016310,0019233,0019902,0030278,0030509,0030641,0030878,0031143,0031281,0031663,0032206,0032496,0032872,0033554,0034198,0035556,0038083,0038133,0042473,0042552,0042770,0042802,0043330,0045944,0048009,0048538,0050804,0051090,0051216,0051403,0051493,0060020,0060324,0060425,0060440,0061308,0070161,0070371,0070374,0070498,0070849,0071260,0071356,0072584,0090170,0098792,0098978,0106310,0120041,0140297,1904262,1904417,2000641 Kd=0.213uM -logKd/Ki=6.70, Kd~200nM P27361 25195011 418 VPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPG 4qtb B 1.4 BS01 38Z B 1 A52 Y53 A69 K71 I73 Y81 R84 T85 E88 Q122 D123 M125 E126 L173 C183 D184 A26 Y27 A43 K45 I47 Y55 R58 T59 E62 Q96 D97 M99 E100 L147 C157 D158 D166 K168 S170 N171 D184 T207 D140 K142 S144 N145 D158 T181 2.7.11.24 0000165,0001784,0004672,0004674,0004707,0005515,0005524,0005634,0005635,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005829,0005856,0005886,0005901,0005925,0006351,0006468,0006915,0006974,0008286,0009887,0010759,0014032,0014044,0016020,0016310,0019233,0019902,0030278,0030509,0030641,0030878,0031143,0031281,0031663,0032206,0032496,0032872,0033554,0034198,0035556,0038083,0038133,0042473,0042552,0042770,0042802,0043330,0045944,0048009,0048538,0050804,0051090,0051216,0051403,0051493,0060020,0060324,0060425,0060440,0061308,0070161,0070371,0070374,0070498,0070849,0071260,0071356,0072584,0090170,0098792,0098978,0106310,0120041,0140297,1904262,1904417,2000641 Kd=0.213uM P27361 25195011 412 EVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPG