4qn9 A 2.652 BS01 ZN A 1 H185 H187 H253 D284 H118 H120 H186 D217 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 Q6IQ20 25684574 501 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNN 4qn9 A 2.652 BS02 ZN A 2 D189 H190 D284 H343 D122 H123 D217 H276 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 Q6IQ20 25684574 502 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNN 4qn9 A 2.652 BS03 DXC A 1 W218 K221 C222 W151 K154 C155 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 504 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNN 4qn9 A 2.652 BS04 DXC A 2 Y159 M160 Y92 M93 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 505 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNN 4qn9 A 2.652 BS05 DXC B 2 W218 R257 W151 R190 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 607 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNN 4qn9 B 2.652 BS01 DXC A 1 Y159 M160 Y92 M93 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 504 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS02 DXC A 2 W218 K221 W151 K154 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 505 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS03 DXC B 1 Y188 R257 Y121 R190 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 601 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS04 ZN B 1 H185 H187 H253 D284 H118 H120 H186 D217 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 Q6IQ20 25684574 604 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS05 ZN B 2 D189 H190 D284 H343 D122 H123 D217 H276 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 Q6IQ20 25684574 605 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS06 DXC B 3 K256 L259 K189 L192 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 608 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND 4qn9 B 2.652 BS07 DXC B 4 G161 P162 A348 G94 P95 A281 3.1.4.54 0000139,0001523,0001659,0005634,0005635,0005654,0005737,0005768,0005769,0005794,0008270,0009395,0016020,0016787,0030868,0031901,0032052,0042622,0042734,0042802,0045211,0046872,0048874,0050729,0070062,0070290,0070291,0070292,0090336,0098686,0098793 -logKd/Ki=4.41, Kd=38.5uM Q6IQ20 25684574 610 SKKGKDGRFVNPWPTWKNPSIPNSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNND