4qab A 2.984 BS01 KK2 A 1 Y89 W143 Y185 C188 Y192 Y97 W151 Y188 C191 Y195 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=9.70, Kd=0.2nM P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab A 2.984 BS02 KK2 E 1 W53 M114 Y164 W61 M122 Y167 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=9.70, Kd=0.2nM P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab B 2.984 BS01 KK2 A 1 W53 R104 M114 W57 R108 M118 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=9.70, Kd=0.2nM P58154 25006260 301 DDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab B 2.984 BS02 KK2 B 1 Y89 W143 Y185 Y192 Y93 W147 Y185 Y192 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=9.70, Kd=0.2nM P58154 25006260 301 DDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab C 2.984 BS01 KK2 B 1 W53 R104 M114 W60 R111 M121 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab C 2.984 BS02 KK2 C 1 Y89 W143 Y185 Y192 Y96 W150 Y187 Y194 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab D 2.984 BS01 KK2 C 1 W53 R104 M114 Y164 W61 R112 M122 Y172 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab D 2.984 BS02 KK2 D 1 Y89 S142 W143 Y185 Y192 Y97 S150 W151 Y193 Y200 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab E 2.984 BS01 KK2 D 1 W53 R104 M114 Y164 W58 R109 M119 Y166 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab E 2.984 BS02 KK2 E 1 Y89 S142 W143 Y185 Y192 Y94 S147 W148 Y187 Y194 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab F 2.984 BS01 KK2 F 1 Y89 W143 T144 Y185 Y192 Y97 W151 T152 Y188 Y195 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab F 2.984 BS02 KK2 J 1 W53 R104 M114 Y164 W61 R112 M122 Y167 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab G 2.984 BS01 KK2 F 1 W53 M114 Y164 W61 M122 Y169 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab G 2.984 BS02 KK2 G 1 Y89 W143 Y185 Y192 Y97 W151 Y190 Y197 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab H 2.984 BS01 KK2 G 1 R104 M114 Y164 R111 M121 Y168 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab H 2.984 BS02 KK2 H 1 Y89 W143 Y185 Y192 Y96 W150 Y189 Y196 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab I 2.984 BS01 KK2 H 1 W53 R104 M114 Y164 W61 R112 M122 Y168 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab I 2.984 BS02 KK2 I 1 Y89 W143 Y185 Y192 Y97 W151 Y189 Y196 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab J 2.984 BS01 KK2 I 1 W53 L112 M114 Y164 W60 L119 M121 Y166 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4qab J 2.984 BS02 KK2 J 1 Y89 W143 Y185 Y192 Y96 W150 Y187 Y194 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 P58154 25006260 301 YKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG