4q23 A 1.98 BS01 RIS A 1 L100 D103 R112 Q171 K200 D243 K257 L88 D91 R100 Q159 K188 D231 K245 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 IC50=11nM, Ki=82.2nM P14324 901 VYAQEKQDFVQHFSQIVRVLTGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY 4q23 A 1.98 BS02 MG A 1 D103 D107 D91 D95 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 902 VYAQEKQDFVQHFSQIVRVLTGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY 4q23 A 1.98 BS03 MG A 2 D103 D107 D91 D95 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 904 VYAQEKQDFVQHFSQIVRVLTGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY