4pns A 1.65 BS01 ZN A 1 C1081 H1084 C1089 C1092 C118 H121 C126 C129 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns A 1.65 BS02 32Y A 1 H1031 G1032 Y1060 S1068 Y1071 H70 G71 Y97 S105 Y108 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=4.52, IC50>30uM Q9H2K2 25286857 1202 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns B 1.65 BS01 ZN B 1 C1081 H1084 C1089 C1092 C124 H127 C132 C135 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 LYFQGDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns B 1.65 BS02 32Y B 1 H1031 G1032 Y1060 S1068 Y1071 E1138 H75 G76 Y103 S111 Y114 E178 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1202 LYFQGDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns C 1.65 BS01 ZN C 1 C1081 H1084 C1089 C1092 C129 H132 C137 C140 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1201 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns C 1.65 BS02 32Y C 1 H1031 G1032 Y1060 S1068 Y1071 H79 G80 Y108 S116 Y119 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1202 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns D 1.65 BS01 ZN D 1 C1081 H1084 C1089 C1092 C117 H120 C125 C128 2.4.2.-,2.4.2.30 0003950 Q9H2K2 25286857 1200 FQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPLAEYVIYRGEQAYPEYLITYQIMRP