4pdk A 2.8 BS01 3VV A 1 L101 L102 A103 R105 T106 I108 L208 Y212 V215 G216 Y219 R253 G256 S259 G260 L94 L95 A96 R98 T99 I101 L201 Y205 V208 G209 Y212 R246 G249 S252 G253 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 301 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQM 4pdk A 2.8 BS02 3VV A 2 N130 Y153 K156 Y184 M187 R191 F194 H195 I200 L203 N123 Y146 K149 Y177 M180 R184 F187 H188 I193 L196 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 302 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQM 4pdk A 2.8 BS03 3VV B 1 I111 R114 Y115 I104 R107 Y108 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 301 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQM 4pdk A 2.8 BS04 3VV B 2 P27 M75 P20 M68 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 302 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQM 4pdk B 2.8 BS01 3VV A 2 W21 I82 W14 I75 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 302 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQMKMTLPS 4pdk B 2.8 BS02 3VV B 1 L101 L102 A104 R105 T106 L208 Y212 V215 G216 Y219 R253 G256 I257 S259 G260 L94 L95 A97 R98 T99 L201 Y205 V208 G209 Y212 R246 G249 I250 S252 G253 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 301 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQMKMTLPS 4pdk B 2.8 BS03 3VV B 2 R126 N130 Y153 Y184 M187 R191 F194 L203 I204 L208 R119 N123 Y146 Y177 M180 R184 F187 L196 I197 L201 ? 0000062,0003677,0003700,0005737,0006355,0006631,0019217,0071072 -logKd/Ki=8.22, Kd=6nM Q9KQU8 25607896 302 PAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQMKMTLPS