4od0 A 2.92 BS01 MG A 1 D9 D11 D185 D9 D11 D185 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 P34913 25079952 602 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4od0 A 2.92 BS02 2RV A 1 F267 D335 W336 Y383 L408 M419 L428 Y466 F267 D335 W336 Y383 L408 M419 L428 Y466 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 -logKd/Ki=9.04, Ki=0.91nM IC50=3.7nM, Ki=0.910nM P34913 25079952 603 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR