4o12 A 2.498 BS01 2QG A 1 Y188 H191 F193 R196 D219 V242 S275 R311 Y172 H175 F177 R180 D203 V226 S259 R295 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 ic50=0.002uM -logKd/Ki=8.70, IC50=0.002uM P43490 24797455 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA 4o12 B 2.498 BS01 2QG A 1 D16 Y18 D9 Y11 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 ic50=0.002uM -logKd/Ki=8.70, IC50=0.002uM P43490 24797455 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA 4o12 B 2.498 BS02 2QG B 1 H191 F193 R196 D219 V242 A244 S275 I309 R311 R349 I351 I378 A379 H174 F176 R179 D202 V225 A227 S258 I292 R294 R332 I334 I361 A362 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 ic50=0.002uM -logKd/Ki=8.70, IC50=0.002uM P43490 24797455 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA