4mk1 A 1.85 BS01 MN A 1 H41 D108 E119 I120 H46 D113 E124 I125 3.1.-.- 0003723,0039694 M9V5A4 23978130 301 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 4mk1 A 1.85 BS02 MN A 2 E80 D108 E85 D113 3.1.-.- 0003723,0039694 M9V5A4 23978130 302 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 4mk1 A 1.85 BS03 27Y A 1 H41 E80 D108 E119 K134 H46 E85 D113 E124 K139 3.1.-.- 0003723,0039694 ic50=16uM -logKd/Ki=4.80, IC50=16uM M9V5A4 23978130 307 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 4mk1 A 1.85 BS04 27Y A 2 A20 Y24 E26 E80 A25 Y29 E31 E85 3.1.-.- 0003723,0039694 ic50=16uM -logKd/Ki=4.80, IC50=16uM M9V5A4 23978130 308 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 4mk1 A 1.85 BS05 27Y A 3 A20 E23 Y24 G81 R82 D83 A25 E28 Y29 G86 R87 D88 3.1.-.- 0003723,0039694 ic50=16uM -logKd/Ki=4.80, IC50=16uM M9V5A4 23978130 309 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE