4loo A 1.95 BS01 peptide B 0 A111 I116 Q120 L122 D125 H126 N159 E160 L217 T218 V273 F274 I275 G276 A277 N278 A107 I112 Q116 L118 D121 H122 N155 E156 L213 T214 V269 F270 I271 G272 A273 N274 D150 K152 N155 D168 T185 D146 K148 N151 D164 T181 2.7.11.24 0000077,0000165,0000902,0000922,0001502,0001525,0001649,0001890,0002021,0002062,0004672,0004674,0004707,0005515,0005524,0005634,0005654,0005737,0005739,0005829,0006006,0006355,0006357,0006366,0006468,0006915,0006974,0007178,0007519,0010628,0010831,0016301,0016310,0016607,0018105,0019395,0019899,0019903,0030278,0030316,0031098,0031281,0031663,0032495,0032496,0032735,0032868,0035331,0035556,0035924,0035994,0038066,0042307,0042770,0045648,0045663,0045944,0046323,0046326,0048010,0048273,0048863,0051146,0051403,0051525,0060045,0060348,0071222,0071223,0071356,0071479,0071493,0090090,0090336,0090400,0098586,0098978,0099179,0106310,1900015,1901741,2000379 P47811 24037507 384 ~ 411 RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 4loo A 1.95 BS02 SB4 A 1 V38 A51 K53 L104 V105 T106 M109 L167 V34 A47 K49 L100 V101 T102 M105 L163 D150 K152 N155 D168 T185 D146 K148 N151 D164 T181 2.7.11.24 0000077,0000165,0000902,0000922,0001502,0001525,0001649,0001890,0002021,0002062,0004672,0004674,0004707,0005515,0005524,0005634,0005654,0005737,0005739,0005829,0006006,0006355,0006357,0006366,0006468,0006915,0006974,0007178,0007519,0010628,0010831,0016301,0016310,0016607,0018105,0019395,0019899,0019903,0030278,0030316,0031098,0031281,0031663,0032495,0032496,0032735,0032868,0035331,0035556,0035924,0035994,0038066,0042307,0042770,0045648,0045663,0045944,0046323,0046326,0048010,0048273,0048863,0051146,0051403,0051525,0060045,0060348,0071222,0071223,0071356,0071479,0071493,0090090,0090336,0090400,0098586,0098978,0099179,0106310,1900015,1901741,2000379 -logKd/Ki=8.15, Kd=7nM P47811 24037507 401 RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL