4lnb B 1.752 BS01 FPP B 1 R274 Y277 H333 A335 R381 K384 Y390 W393 R185 Y188 H244 A246 R292 K295 Y301 W304 H333 R381 K384 D387 C389 Y390 D445 D452 H455 H244 R292 K295 D298 C300 Y301 D353 D360 H363 2.5.1.58 0003824,0004659,0004660,0005965,0008270,0008318,0016853,0018343,0046872,0097354 Q4WPS9 24347326 601 VHPGIPALFREPPLIHDLLSTETTELQSETVNKCLPLLKGIHNSQKGPFNKYGIPALQRKDHLEYLYDSLEDYPASFVALDASRPWMVYWALAGLCLLGEDVTRFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCAMVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLARSSVGNLYSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTVQYYHYCTDSSVSSKFSSAFSWKHDPNFASDGQGSDIGVFTENDRLVPFHPIFVIPHKSAEDIRVWFENQSFDL 4lnb B 1.752 BS02 ZN B 1 D387 C389 H455 D298 C300 H363 H333 R381 K384 D387 C389 Y390 D445 D452 H455 H244 R292 K295 D298 C300 Y301 D353 D360 H363 2.5.1.58 0003824,0004659,0004660,0005965,0008270,0008318,0016853,0018343,0046872,0097354 Q4WPS9 24347326 602 VHPGIPALFREPPLIHDLLSTETTELQSETVNKCLPLLKGIHNSQKGPFNKYGIPALQRKDHLEYLYDSLEDYPASFVALDASRPWMVYWALAGLCLLGEDVTRFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCAMVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLARSSVGNLYSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTVQYYHYCTDSSVSSKFSSAFSWKHDPNFASDGQGSDIGVFTENDRLVPFHPIFVIPHKSAEDIRVWFENQSFDL 4lnb B 1.752 BS03 ED5 B 1 A168 L169 R274 D387 C389 D452 Y454 H455 A79 L80 R185 D298 C300 D360 Y362 H363 H333 R381 K384 D387 C389 Y390 D445 D452 H455 H244 R292 K295 D298 C300 Y301 D353 D360 H363 2.5.1.58 0003824,0004659,0004660,0005965,0008270,0008318,0016853,0018343,0046872,0097354 -logKd/Ki=6.56, IC50=275nM Q4WPS9 24347326 603 VHPGIPALFREPPLIHDLLSTETTELQSETVNKCLPLLKGIHNSQKGPFNKYGIPALQRKDHLEYLYDSLEDYPASFVALDASRPWMVYWALAGLCLLGEDVTRFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCAMVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLARSSVGNLYSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTVQYYHYCTDSSVSSKFSSAFSWKHDPNFASDGQGSDIGVFTENDRLVPFHPIFVIPHKSAEDIRVWFENQSFDL