4kww A 2.55 BS01 PHT A 1 T137 R138 H160 R161 M169 K171 T136 R137 H159 R160 M168 K170 R102 K139 K171 E201 D222 R101 K138 K170 E200 D221 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 -logKd/Ki=5.55, Ki=2.8uM Q15274 24038671 300 DAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF 4kww B 2.55 BS01 PHT B 1 T137 R138 H160 R161 M169 K171 T136 R137 H159 R160 M168 K170 R102 K139 K171 E201 D222 R101 K138 K170 E200 D221 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 -logKd/Ki=5.55, Ki=2.8uM Q15274 24038671 300 DAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF 4kww C 2.55 BS01 PHT C 1 T137 R138 H160 R161 M169 K171 T136 R137 H159 R160 M168 K170 R102 K139 K171 E201 D222 R101 K138 K170 E200 D221 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 -logKd/Ki=5.55, Ki=2.8uM Q15274 24038671 300 DAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF 4kww D 2.55 BS01 PHT D 1 T137 R138 H160 R161 M169 K171 T135 R136 H158 R159 M167 K169 R102 K139 K171 E201 D222 R100 K137 K169 E199 D220 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 Q15274 24038671 300 AEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF 4kww E 2.55 BS01 PHT E 1 T137 R138 H160 R161 M169 K171 T135 R136 H158 R159 M167 K169 R102 K139 K171 E201 D222 R100 K137 K169 E199 D220 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 Q15274 24038671 300 AEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF 4kww F 2.55 BS01 PHT F 1 T137 R138 H160 R161 M169 K171 T136 R137 H159 R160 M168 K170 R102 K139 K171 E201 D222 R101 K138 K170 E200 D221 2.4.2.19 0004514,0005515,0005737,0005829,0009435,0016757,0016763,0019363,0019674,0034213,0042802,0070062,1902494 Q15274 24038671 300 DAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLF