4kfo A 1.6 BS01 1QS A 1 Y188 H191 F193 R196 D219 V242 A244 R311 I351 Y173 H176 F178 R181 D204 V227 A229 R296 I336 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 IC50=5.0nM, EC50=1.1nM P43490 23617784 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELE 4kfo A 1.6 BS02 1QS B 1 D16 Y18 D9 Y11 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 IC50=5.0nM, EC50=1.1nM P43490 23617784 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELE 4kfo B 1.6 BS01 1QS A 1 D16 Y18 D9 Y11 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 IC50=5.0nM, EC50=1.1nM P43490 23617784 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIEL 4kfo B 1.6 BS02 1QS B 1 Y188 H191 F193 R196 D219 V242 A244 I309 R311 I351 Y172 H175 F177 R180 D203 V226 A228 I293 R295 I335 2.4.2.12 0005125,0005515,0005576,0005615,0005634,0005737,0005829,0007165,0007267,0007623,0008284,0008286,0009435,0016607,0016757,0019363,0030054,0032922,0034356,0042802,0045944,0047280,0048511,0051770,0060612,0070062 IC50=5.0nM, EC50=1.1nM P43490 23617784 601 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIEL