4jvn A 2.05 BS01 YUG A 1 Y20 P46 F80 C83 K105 H107 F141 V145 Y239 I246 Y18 P44 F78 C81 K103 H105 F139 V143 Y237 I244 K47 H107 S137 K45 H105 S135 2.8.2.4 0004062,0004304,0005496,0005515,0005737,0005829,0006068,0006629,0006711,0008146,0008202,0008210,0016740,0031965,0045600,0047894,0050294,0050427,0051923 ic50=23nM P49888 23959441 501 SELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTE 4jvn A 2.05 BS02 A3P A 1 K47 G49 T50 T51 W52 R129 S137 Y192 F228 M255 R256 K257 G258 K45 G47 T48 T49 W50 R127 S135 Y190 F226 M253 R254 K255 G256 K47 H107 S137 K45 H105 S135 2.8.2.4 0004062,0004304,0005496,0005515,0005737,0005829,0006068,0006629,0006711,0008146,0008202,0008210,0016740,0031965,0045600,0047894,0050294,0050427,0051923 P49888 23959441 502 SELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTE 4jvn B 2.05 BS01 YUG B 1 P46 F80 K105 H107 F141 Y239 P44 F78 K103 H105 F139 Y237 K47 H107 S137 K45 H105 S135 2.8.2.4 0004062,0004304,0005496,0005515,0005737,0005829,0006068,0006629,0006711,0008146,0008202,0008210,0016740,0031965,0045600,0047894,0050294,0050427,0051923 ic50=23nM P49888 23959441 301 SELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTE 4jvn B 2.05 BS02 A3P B 1 K47 G49 T50 T51 W52 R129 S137 Y192 F228 M255 R256 K257 G258 K45 G47 T48 T49 W50 R127 S135 Y190 F226 M253 R254 K255 G256 K47 H107 S137 K45 H105 S135 2.8.2.4 0004062,0004304,0005496,0005515,0005737,0005829,0006068,0006629,0006711,0008146,0008202,0008210,0016740,0031965,0045600,0047894,0050294,0050427,0051923 P49888 23959441 302 SELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTE