4jq4 A 1.52 BS01 IMN A 1 Y55 H117 W227 L306 L308 Y52 H114 W224 L303 L305 D50 Y55 K84 H117 D47 Y52 K81 H114 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 IC50=75000nM, Ki=>100000nM P52895 401 KYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 4jq4 A 1.52 BS02 NAP A 1 G22 T23 Y24 D50 Y55 Q190 Y216 S217 L219 S221 H222 A253 L268 K270 S271 R276 Q279 N280 G19 T20 Y21 D47 Y52 Q187 Y213 S214 L216 S218 H219 A250 L265 K267 S268 R273 Q276 N277 D50 Y55 K84 H117 D47 Y52 K81 H114 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 402 KYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 4jq4 B 1.52 BS01 IMN B 1 Y55 H117 I129 W227 L306 L308 Y53 H115 I127 W222 L301 L303 D50 Y55 K84 H117 D48 Y53 K82 H115 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 IC50=75000nM, Ki=>100000nM P52895 401 SKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 4jq4 B 1.52 BS02 NAP B 1 G22 T23 Y24 D50 Y55 H117 Q190 Y216 S217 L219 S221 A253 L268 K270 S271 Y272 R276 Q279 N280 G20 T21 Y22 D48 Y53 H115 Q188 Y214 S215 L217 S219 A248 L263 K265 S266 Y267 R271 Q274 N275 D50 Y55 K84 H117 D48 Y53 K82 H115 1.-.-.-,1.1.1.112,1.1.1.209,1.1.1.357,1.1.1.53,1.1.1.62,1.3.1.20 0004032,0004303,0005737,0005829,0006693,0007186,0007586,0008202,0008284,0016491,0016655,0030855,0031406,0032052,0042448,0044597,0044598,0047023,0047044,0047086,0047115,0047718,0051897,0071395,0071799 P52895 402 SKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF