4ja1 A 1.96 BS01 ZN A 1 H201 H205 H211 H119 H123 H129 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 301 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 A 1.96 BS02 ZN A 2 H151 D153 H166 H179 H69 D71 H84 H97 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 302 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 A 1.96 BS03 CA A 1 D158 G159 G161 V163 D181 E184 D76 G77 G79 V81 D99 E102 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 303 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 A 1.96 BS04 CA A 2 D141 G173 N175 D177 D59 G91 N93 D95 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 304 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 A 1.96 BS05 CA A 3 D107 D182 E184 D25 D100 E102 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 305 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 A 1.96 BS06 PT A 1 E139 M143 E57 M61 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 306 FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP 4ja1 B 1.96 BS01 ZN B 1 H201 H205 H211 H113 H117 H123 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 301 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS02 ZN B 2 H151 D153 H166 H179 H63 D65 H78 H91 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 302 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS03 CA B 1 D158 G159 G161 V163 D181 E184 D70 G71 G73 V75 D93 E96 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 303 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS04 CA B 2 D141 G173 N175 D177 D53 G85 N87 D89 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 304 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS05 CA B 3 D107 D182 E184 D19 D94 E96 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 305 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS06 NGH B 1 V163 L164 A165 H201 E202 H205 H211 V75 L76 A77 H113 E114 H117 H123 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 Ki=132nM, IC50=6500nM P08254 23660647 306 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET 4ja1 B 1.96 BS07 PT B 1 E139 M143 E51 M55 H201 E202 H205 H211 H113 E114 H117 H123 3.4.24.17 0004222,0006508,0008237,0008270,0031012 P08254 23660647 307 IPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPET