4ith	A	2.25	BS01	RCM	A	1	M67 L70 V75 V76 M92 H136 I154 A155 D156 S161 F162	M39 L42 V47 V48 M64 H108 I126 A127 D128 S133 F134	D138 K140 E142 N143 D156 T189	D110 K112 E114 N115 D128 T142	2.7.11.1	0004672,0005524,0006468		ic50=0.3169uM	-logKd/Ki=6.50, IC50=316.9nM	IC50=200nM, EC50=18nM	Q13546	23473668	307 	NVIKMKSSDFLVSLAFHRTQGLMIMKTVNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE
4ith	B	2.25	BS01	RCM	B	1	M67 L70 V75 V76 L78 M92 A155 D156 S161 F162	M55 L58 V63 V64 L66 M80 A143 D144 S149 F150	D138 K140 E142 N143 D156 T189	D126 K128 E130 N131 D144 T165	2.7.11.1	0004672,0005524,0006468		ic50=0.3169uM		IC50=200nM, EC50=18nM	Q13546	23473668	307 	LNVIKMKSSDFLESAELKVSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNEGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE