4i5c A 2.1 BS01 C5I A 1 L881 G882 E883 G884 G887 V889 A906 M956 E957 F958 L959 L1010 D1021 L17 G18 E19 G20 G23 V25 A42 M84 E85 F86 L87 L138 D149 D1003 A1005 R1007 N1008 D1021 D1040 D131 A133 R135 N136 D149 D167 2.7.10.2 0004672,0004713,0005524,0006468 Ki=1.5nM -logKd/Ki=8.82, Ki=1.5nM Ki=1.5nM, EC50=114nM P23458 23642482 1201 VDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPNHIADLKKEIEILRNLYHENIVKYKGICTNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK 4i5c B 2.1 BS01 C5I B 1 L881 G882 E883 G884 G887 K888 V889 A906 M956 E957 F958 L959 N1008 L1010 D1021 L29 G30 E31 G32 G35 K36 V37 A54 M95 E96 F97 L98 N147 L149 D160 D1003 A1005 R1007 N1008 D1021 D1040 D142 A144 R146 N147 D160 D179 2.7.10.2 0004672,0004713,0005524,0006468 Ki=1.5nM Ki=1.5nM, EC50=114nM P23458 23642482 1205 GDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPHIADLKKEIEILRNLYHENIVKYKGICTEGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK