4h81 A 2.05 BS01 ADP A 1 N249 A253 I290 V298 T304 T305 G335 G337 G339 L340 N207 A211 I248 V256 T262 T263 G265 G267 G269 L270 Y241 E245 K248 N249 Y199 E203 K206 N207 2.7.11.1,2.7.11.4 0004672,0004674,0004722,0004740,0005524,0005739,0005759,0006550,0006552,0006574,0007283,0008610,0009083,0010906,0016301,0016310,0016772,0045252,0047323,0106310 Q00972 23716694 401 TMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI 4h81 A 2.05 BS02 WJ2 A 1 I72 Y99 L128 H132 R167 I170 R171 I30 Y57 L86 H90 R125 I128 R129 Y241 E245 K248 N249 Y199 E203 K206 N207 2.7.11.1,2.7.11.4 0004672,0004674,0004722,0004740,0005524,0005739,0005759,0006550,0006552,0006574,0007283,0008610,0009083,0010906,0016301,0016310,0016772,0045252,0047323,0106310 -logKd/Ki=5.12, Kd=7.5uM Q00972 23716694 404 TMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI