4gu6 A 1.95 BS01 10N A 1 E430 L501 C502 G505 N551 L553 D564 E17 L86 C87 G90 N136 L138 D149 D546 A548 R550 N551 D564 D131 A133 R135 N136 D149 2.7.10.2 0004672,0004713,0005524,0006468 Kd=44nM -logKd/Ki=7.36, Kd=44nM IC50=195nM, Kd=44nM Q05397 23294348 701 DYEIQRERIELGRCIGEGQFGDVHQGIYMSNPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQ 4gu6 B 1.95 BS01 10N B 1 I428 E430 L501 C502 G505 E506 N551 L553 D564 L567 I14 E16 L87 C88 G91 E92 N137 L139 D150 L153 D546 A548 R550 N551 D564 D132 A134 R136 N137 D150 2.7.10.2 0004672,0004713,0005524,0006468 Kd=44nM IC50=195nM, Kd=44nM Q05397 23294348 701 YEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQ