4gr8 A 1.299 BS01 ZN A 1 H218 H222 H228 H108 H112 H118 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 23343195 301 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY 4gr8 A 1.299 BS02 ZN A 2 H168 D170 H183 H196 H58 D60 H73 H86 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 23343195 302 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY 4gr8 A 1.299 BS03 CA A 1 D158 G190 G192 D194 D48 G80 G82 D84 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 23343195 303 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY 4gr8 A 1.299 BS04 CA A 2 D124 E199 E201 D14 E89 E91 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 23343195 304 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY 4gr8 A 1.299 BS05 CA A 3 D175 G176 G178 I180 D198 E201 D65 G66 G68 I70 D88 E91 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 23343195 305 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY 4gr8 A 1.299 BS06 R4C A 1 G179 L181 A182 H183 T215 H218 E219 H222 H228 V235 F237 T239 Y240 G69 L71 A72 H73 T105 H108 E109 H112 H118 V125 F127 T129 Y130 H218 E219 H222 H228 H108 E109 H112 H118 3.4.24.65 0004222,0006508,0008237,0008270,0031012 Ki=14.7nM -logKd/Ki=7.83, Ki=14.7nM Ki=15nM P39900 23343195 306 KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY