4gh8 A 1.85 BS01 MTX A 1 I5 A6 M20 D28 F32 K33 N55 R61 I5 A6 M20 D28 F32 K33 N55 R61 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 IC50=8.8nM, EC50=1nM P0ABQ4 23733948 201 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 A 1.85 BS02 NDP A 1 A6 A7 I14 N18 A19 G44 R45 H46 T47 L66 S67 S68 K80 I98 G100 G101 R102 V103 Q106 A6 A7 I14 N18 A19 G44 R45 H46 T47 L66 S67 S68 K80 I98 G100 G101 R102 V103 Q106 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 Kd=2.6uM P0ABQ4 23733948 202 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 A 1.85 BS03 CA A 1 D131 E133 D131 E133 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 P0ABQ4 23733948 203 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 A 1.85 BS04 CA A 2 E53 R56 E53 R56 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 P0ABQ4 23733948 204 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 B 1.85 BS01 MTX B 1 I5 A6 A7 M20 D28 L29 F32 K33 P52 N55 R61 I5 A6 A7 M20 D28 L29 F32 K33 P52 N55 R61 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 IC50=8.8nM, EC50=1nM P0ABQ4 23733948 201 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 B 1.85 BS02 NDP B 1 A6 A7 I14 N18 A19 G44 R45 H46 T47 L66 S67 S68 K80 I98 G100 G101 R102 V103 Q106 A6 A7 I14 N18 A19 G44 R45 H46 T47 L66 S67 S68 K80 I98 G100 G101 R102 V103 Q106 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 Kd=2.6uM P0ABQ4 23733948 202 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER 4gh8 B 1.85 BS03 CA B 1 E53 R56 E53 R56 I5 M20 W22 D28 L29 F32 L58 I95 T117 I5 M20 W22 D28 L29 F32 L58 I95 T117 1.5.1.3 0004146,0046654,0050661 P0ABQ4 23733948 203 MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIPEKNRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER