4ge9 A 2.43 BS01 0L0 A 1 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 -logKd/Ki=8.80, Ki=1.6nM Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 A 2.43 BS02 0L0 B 1 I19 R20 T23 G39 L40 Y74 S75 S77 L293 I19 R20 T23 G39 L40 Y74 S75 S77 L293 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 -logKd/Ki=8.80, Ki=1.6nM Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 B 2.43 BS01 0L0 A 1 I19 R20 T23 G39 Y74 S75 S77 I19 R20 T23 G39 Y74 S75 S77 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 -logKd/Ki=8.80, Ki=1.6nM Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 B 2.43 BS02 0L0 B 1 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 -logKd/Ki=8.80, Ki=1.6nM Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 C 2.43 BS01 0L0 C 1 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 C 2.43 BS02 0L0 D 1 I19 R20 T23 G39 L40 Y74 S75 S77 L293 I19 R20 T23 G39 L40 Y74 S75 S77 L293 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 D 2.43 BS01 0L0 C 1 I19 R20 T23 G39 L40 Y74 S75 S77 L293 I19 R20 T23 G39 L40 Y74 S75 S77 L293 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP 4ge9 D 2.43 BS02 0L0 D 1 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 S117 Q118 Y142 N202 D230 P232 Y233 S260 S262 R270 R399 2.6.1.39,2.6.1.4,2.6.1.63,2.6.1.7,2.6.1.73 0005739,0005759,0006103,0006536,0008483,0009058,0016212,0030170,0033512,0042803,0047315,0047536,0047958,0050094,0070189,1901605 Q8N5Z0 24900560 4000 MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESLLVP