4flj A 1.74 BS01 MN A 1 D240 H303 T334 E336 E367 D151 H214 T245 E247 E278 D229 D240 H303 H310 E336 E367 D140 D151 H214 H221 E247 E278 3.4.11.18 0006508,0070006 P53582 22913487 501 YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS 4flj A 1.74 BS02 MN A 2 D229 D240 E367 D140 D151 E278 D229 D240 H303 H310 E336 E367 D140 D151 H214 H221 E247 E278 3.4.11.18 0006508,0070006 P53582 22913487 502 YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS 4flj A 1.74 BS03 Y08 A 1 Y195 H212 D229 D240 C301 H303 F309 H310 E336 E367 Y106 H123 D140 D151 C212 H214 F220 H221 E247 E278 D229 D240 H303 H310 E336 E367 D140 D151 H214 H221 E247 E278 3.4.11.18 0006508,0070006 ic50=7.45uM -logKd/Ki=5.13, IC50=7.45uM P53582 22913487 503 YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS