4ehm B 2.2 BS01 PJA A 1 R144 G192 Q193 W244 F289 R138 G186 Q187 W238 F283 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H184 R226 K229 D232 C234 Y235 D274 D281 H284 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 -logKd/Ki=5.85, IC50=1.4uM Q08603 22480322 401 QKDVTIKSDAPDTLLLEKHADYIASYGSDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 4ehm B 2.2 BS02 ZN B 1 D238 C240 H290 D232 C234 H284 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H184 R226 K229 D232 C234 Y235 D274 D281 H284 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 22480322 401 QKDVTIKSDAPDTLLLEKHADYIASYGSDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 4ehm B 2.2 BS03 CA B 1 H64 M66 H58 M60 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H184 R226 K229 D232 C234 Y235 D274 D281 H284 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 22480322 402 QKDVTIKSDAPDTLLLEKHADYIASYGSDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS