4dfr A 1.7 BS01 MTX A 1 I5 A6 D27 F31 K32 I50 R52 L54 R57 I94 I5 A6 D27 F31 K32 I50 R52 L54 R57 I94 I5 M20 W22 D27 L28 F31 L54 I91 T113 I5 M20 W22 D27 L28 F31 L54 I91 T113 1.5.1.3 0004146,0005515,0005542,0005829,0006730,0009257,0009410,0016491,0031427,0046452,0046654,0046655,0046656,0046677,0050661,0051870,0051871,0070401,0070402 IC50=8.8nM, EC50=1nM P0ABQ4 6815178 161 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFKILERR 4dfr B 1.7 BS01 MTX B 1 I5 A6 A7 D27 L28 F31 K32 I50 R52 L54 R57 I94 I5 A6 A7 D27 L28 F31 K32 I50 R52 L54 R57 I94 I5 M20 W22 D27 L28 F31 L54 I91 T113 I5 M20 W22 D27 L28 F31 L54 I91 T113 1.5.1.3 0004146,0005515,0005542,0005829,0006730,0009257,0009410,0016491,0031427,0046452,0046654,0046655,0046656,0046677,0050661,0051870,0051871,0070401,0070402 IC50=8.8nM, EC50=1nM P0ABQ4 6815178 162 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFKILERR