4c2z	A	2.08	BS01	MYA	A	1	Y117 Q118 F119 W120 Y180 V181 I245 L248 C249 V250 R255 S256 R258 V259 A260 T268 V271 F277 A279 Y281 T282 L287 Y479	Y3 Q4 F5 W6 Y66 V67 I131 L134 C135 V136 R141 S142 R144 V145 A146 T154 V157 F163 A165 Y167 T168 L173 Y365	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499					P30419	25255805	1497 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
4c2z	A	2.08	BS02	646	A	1	V181 D183 F190 N246 G284 Y296 H298 F311 S405 Y420 D471 Q496	V67 D69 F76 N132 G170 Y182 H184 F197 S291 Y306 D357 Q382	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499		ic50=17nM		Ki=11nM, IC50=4.0nM	P30419	25255805	1498 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
4c2z	A	2.08	BS03	MG	A	1	L254 R255 S256 K257 V259	L140 R141 S142 K143 V145	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499					P30419	25255805	1499 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
4c2z	B	2.08	BS01	MYA	B	1	Y117 F119 W120 Y180 V181 I245 N246 L248 V250 R255 S256 R258 V259 A260 T268 V271 H272 A279 Y281 T282 L287 Y479	Y3 F5 W6 Y66 V67 I131 N132 L134 V136 R141 S142 R144 V145 A146 T154 V157 H158 A165 Y167 T168 L173 Y365	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499					P30419	25255805	1497 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
4c2z	B	2.08	BS02	646	B	1	V181 E182 D183 F190 N246 T282 G284 Y296 H298 F311 Y420 Q496	V67 E68 D69 F76 N132 T168 G170 Y182 H184 F197 Y306 Q382	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499		ic50=17nM		Ki=11nM, IC50=4.0nM	P30419	25255805	1498 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
4c2z	B	2.08	BS03	MG	B	1	S256 K257 V259	S142 K143 V145	N246 F247 L248 T282 Q496	N132 F133 L134 T168 Q382	2.3.1.-,2.3.1.97	0004379,0006499					P30419	25255805	1499 	RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ