4btu B 2.37 BS01 CA B 1 D70 N72 Q75 E76 E77 E80 D56 N58 Q61 E62 E63 E66 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 P00742 24175584 1245 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4btu B 2.37 BS02 6XS B 1 Y99 F174 A190 Q192 V213 W215 G216 G219 C220 Y228 Y85 F162 A180 Q182 V203 W205 G206 G208 C209 Y218 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 ic50=0.5nM -logKd/Ki=9.30, IC50=0.5nM IC50=0.500000nM P00742 24175584 1246 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4btu F 2.37 BS01 CA F 1 D70 N72 Q75 E76 E77 E80 D56 N58 Q61 E62 E63 E66 G193 S195 G196 G183 S185 G186 3.4.21.6 0004252,0006508 P00742 24175584 1245 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4btu F 2.37 BS02 6XS F 1 H57 E97 T98 Y99 A190 Q192 V213 W215 G216 G219 I227 Y228 H42 E83 T84 Y85 A180 Q182 V203 W205 G206 G208 I217 Y218 G193 S195 G196 G183 S185 G186 3.4.21.6 0004252,0006508 ic50=0.5nM IC50=0.500000nM P00742 24175584 1246 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT