4bo3 A 2.5 BS01 U98 A 1 W106 F107 V110 N111 L114 A156 G160 F164 W94 F95 V98 N99 L102 A142 G146 F150 G16 S141 Y154 K158 G16 S129 Y140 K144 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.3uM -logKd/Ki=6.52, IC50=0.30uM O54438 24015914 1248 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo3 B 2.5 BS01 U98 A 1 L114 G163 F164 L100 G145 F146 G16 S141 Y154 K158 G15 S127 Y136 K140 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 -logKd/Ki=6.52, IC50=0.30uM O54438 24015914 1248 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo3 C 2.5 BS01 U98 C 1 W106 F107 N111 L114 A156 A159 G160 W104 F105 N109 L112 A151 A154 G155 G16 S141 Y154 K158 G22 S139 Y149 K153 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.3uM O54438 24015914 1248 NLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo3 D 2.5 BS01 U98 C 1 L114 G163 F164 L106 G149 F150 G16 S141 Y154 K158 G20 S133 Y140 K144 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 O54438 24015914 1248 YFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNADDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTREAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS