4bo2 A 1.9 BS01 36K A 1 W106 V110 N111 L114 A156 G163 F164 W97 V101 N102 L105 A147 G154 F155 G16 S141 Y154 K158 G20 S132 Y145 K149 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.05uM -logKd/Ki=7.30, IC50=0.05uM O54438 24015914 1248 YFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo2 B 1.9 BS01 36K A 1 F107 L114 A156 G160 G163 F164 F95 L102 A144 G148 G151 F152 G16 S141 Y154 K158 G15 S129 Y142 K146 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 -logKd/Ki=7.30, IC50=0.05uM O54438 24015914 1248 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGIDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo2 C 1.9 BS01 36K C 1 W106 V110 N111 L114 A159 G160 G163 F164 W99 V103 N104 L107 A152 G153 G156 F157 G16 S141 Y154 K158 G20 S134 Y147 K151 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.05uM O54438 24015914 1248 YFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGIDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo2 D 1.9 BS01 36K C 1 W106 F107 N111 A156 G160 G163 F164 W104 F105 N109 A154 G158 G161 F162 G16 S141 Y154 K158 G21 S139 Y152 K156 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 O54438 24015914 1248 LYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGIRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS