4bo1 A 2.2 BS01 NKH B 1 W106 V110 N111 L114 A156 G160 W100 V104 N105 L108 A146 G150 G16 S141 Y154 K158 G21 S135 Y144 K148 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 -logKd/Ki=7.30, IC50=0.05uM O54438 24015914 1248 LYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo1 B 2.2 BS01 NKH B 1 F107 V110 L114 G160 G163 F94 V97 L101 G142 G145 G16 S141 Y154 K158 G15 S128 Y136 K140 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.05uM -logKd/Ki=7.30, IC50=0.05uM O54438 24015914 1248 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo1 C 2.2 BS01 NKH D 1 W106 V110 N111 L114 A156 W104 V108 N109 L112 A149 G16 S141 Y154 K158 G21 S139 Y147 K151 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 O54438 24015914 1248 LYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bo1 D 2.2 BS01 NKH D 1 W106 F107 V110 L114 G160 G163 F164 W103 F104 V107 L111 G156 G159 F160 G16 S141 Y154 K158 G23 S138 Y150 K154 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.05uM O54438 24015914 1248 ENLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS