4bny A 1.8 BS01 36I B 1 W106 L114 A156 G163 F164 W98 L106 A148 G155 F156 G16 S141 Y154 K158 G17 S133 Y146 K150 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 -logKd/Ki=7.10, Ki=0.08uM O54438 24015914 1248 SMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNARMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bny B 1.8 BS01 36I B 1 W106 F107 V110 L114 G163 F164 W92 F93 V96 L100 G149 F150 G16 S141 Y154 K158 G16 S127 Y140 K144 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.08uM -logKd/Ki=7.10, Ki=0.08uM O54438 24015914 1248 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bny C 1.8 BS01 36I D 1 W106 V110 L114 G160 G163 W112 V116 L120 G166 G169 G16 S141 Y154 K158 G32 S147 Y160 K164 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 O54438 24015914 1248 HHHHHHSSGVNLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bny D 1.8 BS01 36I D 1 F107 V110 N111 L114 A156 G160 F104 V107 N108 L111 A153 G157 G16 S141 Y154 K158 G19 S138 Y151 K155 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.08uM O54438 24015914 1248 FQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGIVRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS