4bge A 2.25 BS01 PYW A 1 I21 A94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 M199 I19 A92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 M197 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge B 2.25 BS01 PYW B 1 I21 A94 I95 G96 M103 M147 D148 F149 Y158 M161 K165 P193 I194 M199 I19 A92 I93 G94 M101 M145 D146 F147 Y156 M159 K163 P191 I192 M197 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge C 2.25 BS01 PYW C 1 I21 A94 G96 M103 M147 D148 F149 A157 Y158 M161 K165 P193 I19 A92 G94 M101 M145 D146 F147 A155 Y156 M159 K163 P191 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIREEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge D 2.25 BS01 PYW D 1 I21 A94 I95 G96 M103 M147 D148 F149 Y158 M161 K165 I194 I215 I19 A92 I93 G94 M101 M145 D146 F147 Y156 M159 K163 I192 I198 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge E 2.25 BS01 PYW E 1 I21 A94 I95 G96 M103 M147 D148 F149 Y158 K165 I19 A92 I93 G94 M101 M145 D146 F147 Y156 K163 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge F 2.25 BS01 PYW F 1 I21 A94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 M199 I19 A92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 M197 Y158 K165 Y156 K163 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 Ki=4800nM, IC50=6000nM P9WGR1 24292073 1270 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL