4b4m A 2.35 BS01 JWT A 1 S41 T42 L45 Y113 G115 V250 A251 E255 I256 R259 S44 T45 L48 Y116 G118 V253 A254 E258 I259 R262 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.205uM -logKd/Ki=6.69, IC50=0.205uM IC50=205nM Q9HU22 23138692 400 HHHMKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b4m B 2.35 BS01 JWT B 1 S41 T42 L45 Y113 G115 H119 V250 A251 E255 R259 S41 T42 L45 Y113 G115 H119 V250 A251 E255 R259 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.205uM IC50=205nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b4m C 2.35 BS01 JWT C 1 S41 T42 L45 Y113 G115 V250 A251 E255 S41 T42 L45 Y113 G115 V250 A251 E255 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.205uM -logKd/Ki=6.69, IC50=0.205uM IC50=205nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b4m D 2.35 BS01 JWT D 1 S41 T42 L45 Y113 G115 V250 A251 E255 S41 T42 L45 Y113 G115 V250 A251 E255 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.205uM IC50=205nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY