4arw A 2.204 BS01 HNR A 1 S41 L45 Y113 Y114 G115 V250 A251 E255 S42 L46 Y114 Y115 G116 V251 A252 E256 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 Kd=0.074uM -logKd/Ki=7.13, Kd=0.074uM IC50=2.1e+2nM Q9HU22 23138692 400 HHHRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4arw B 2.204 BS01 HNR B 1 S41 L45 Y113 Y114 G115 V250 A251 E255 S40 L44 Y112 Y113 G114 V247 A248 E252 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 Kd=0.074uM IC50=2.1e+2nM Q9HU22 23138692 400 KRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4arw C 2.204 BS01 HNR C 1 S41 L45 Y113 Y114 G115 V250 A251 E255 S39 L43 Y111 Y112 G113 V246 A247 E251 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 Kd=0.074uM IC50=2.1e+2nM Q9HU22 23138692 400 RKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4arw D 2.204 BS01 HNR D 1 S41 L45 Y113 Y114 G115 V250 A251 E255 S40 L44 Y112 Y113 G114 V249 A250 E254 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 Kd=0.074uM IC50=2.1e+2nM Q9HU22 23138692 400 KRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY