4aic A 2.05 BS01 FOM A 1 D151 S152 E153 A176 S177 H200 W203 S213 N218 K219 D141 S142 E143 A166 S167 H190 W193 S203 N208 K209 1.1.1.267 0000287,0008299,0016491,0019288,0030145,0030604,0046872,0050897,0051483,0051484,0070402 ic50=80nM IC50=80nM, Ki=140nM, Kd=40nM P9WNS1 17491006 1390 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4aic A 2.05 BS02 NDP A 1 G19 T21 G22 S23 I24 A46 G47 A49 H50 A69 A103 L104 L108 A126 E129 D151 M205 N209 M267 G9 T11 G12 S13 I14 A36 G37 A39 H40 A59 A93 L94 L98 A116 E119 D141 M195 N199 M257 1.1.1.267 0000287,0008299,0016491,0019288,0030145,0030604,0046872,0050897,0051483,0051484,0070402 P9WNS1 17491006 1391 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4aic A 2.05 BS03 MN A 1 D151 E153 E222 D141 E143 E212 1.1.1.267 0000287,0008299,0016491,0019288,0030145,0030604,0046872,0050897,0051483,0051484,0070402 P9WNS1 17491006 1392 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4aic B 2.05 BS01 MN B 1 D151 E153 E222 D141 E143 E212 1.1.1.267 0000287,0008299,0016491,0019288,0030145,0030604,0046872,0050897,0051483,0051484,0070402 P9WNS1 17491006 1390 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4aic B 2.05 BS02 NDP B 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 L108 A126 K128 D151 G9 T11 G12 S13 I14 A36 G37 G38 A39 H40 A59 A93 L94 V95 L98 A116 K118 D141 1.1.1.267 0000287,0008299,0016491,0019288,0030145,0030604,0046872,0050897,0051483,0051484,0070402 P9WNS1 17491006 1392 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM